Caifanes is a Spanish-language rock (Rock en Español) band from Mexico City formed in 1987. They achieved fame throughout the late 1980s and early 1990s. The original lineup consisted of Saúl Hernández (vocals & guitar), Sabo Romo (bass guitar), Alfonso André (drums) and Diego Herrera (keyboards and saxophone). Argentine guitarist Alejandro Marcovich joined in 1989.

Caifanes’ style can be described as a hybrid of British new wave, proggressive rock, and Latin percussion underscored by deep, somber, and Latin American-Mexican-Spanish influenced lyrics and the vocal style of Saúl Hernández. Members of Caifanes have cited King Crimson as a major influence.

The name Caifanes is derived from 1940s Mexican Pachuco (zoot suiter) slang "Cai fan".